Ten-man Arsenal were knocked out of the Champions League at the last-16 stage for the seventh successive season following a second-half capitulation against Bayern Munich.
A debated decision in the 53rd minute shattered any hopes of the Gunners becoming the first side in Champions League history to overturn a four-goal deficit, having also lost the first leg in Germany 5-1
They led through Theo Walcott’s stunning 20th-minute goal, before Bayern were awarded a penalty that also resulted in the sending off of defender Laurent Koscielny.
The France centre-back was initially shown a yellow card by referee Anastasios Sidiropoulos for his foul on Robert Lewandowski inside the area – but it was upgraded to a red once he decided Koscielny made no attempt to win the ball.
Gunners boss Arsene Wenger looked perplexed by the sudden change of heart by the official.
Lewandowski placed his spot-kick beyond the reach of David Ospina to give Bayern a 6-2 aggregate lead and effectively kill off the tie.
The home side then folded as Bayern scored three goals in 12 minutes. Arjen Robben robbed Alexis Sanchez of the ball before Douglas Costa made it 3-1 with a stunning solo goal.
Fellow midfielder Arturo Vidal grabbed a late double, first with an impudent chip before slotting in from Costa’s square pass.
The 10-2 aggregate defeat is the worst suffered by an English side in the Champions League and the defeat was Arsenal’s biggest home loss since November 1998 (5-0 against Chelsea in the League Cup).